- penetrate the blood-brain barrier
Fachwörterbuch Medizin Englisch-Deutsch. 2013.
Fachwörterbuch Medizin Englisch-Deutsch. 2013.
blood-brain barrier — A network of blood vessels with closely spaced cells that makes it difficult for potentially toxic substances (such as anticancer drugs) to penetrate the blood vessel walls and enter the brain … English dictionary of cancer terms
Blood-ocular barrier — The blood ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. It controls the passage of substances from the blood into the eye. It is a physical barrier… … Wikipedia
blood — bloodlike, adj. /blud/, n. 1. the fluid that circulates in the principal vascular system of human beings and other vertebrates, in humans consisting of plasma in which the red blood cells, white blood cells, and platelets are suspended. 2. the… … Universalium
intracerebroventricular — The locus of administration of drugs or chemicals into the ventricular system of the brain. Often used in animal studies and occasionally for the introduction of antiinfectives that do not penetrate the blood brain barrier into the brain in… … Medical dictionary
GDNF family of ligands — The GDNF family of ligands (GFL) consists of four neurotrophic factors: glial cell line derived neurotrophic factor (GDNF) neurturin (NRTN), artemin (ARTN) and persephin (PSPN). GFLs have been shown to play a role in a number of biological… … Wikipedia
Polar surface area — The Polar Surface Area (PSA) is defined as the surface sum over all polar atoms, (usually oxygen and nitrogen), including also attached hydrogens.PSA is a commonly used medicinal chemistry metric for the optimisation of cell permeability.… … Wikipedia
Metastatic breast cancer — is a stage of breast cancer where the disease has spread to distant metastases. It is a complication of primary breast cancer, usually occurring several years after resection of the primary breast cancer. Metastatic breast cancer cells frequently … Wikipedia
Curcumin — IUPAC name (1E,6E) 1,7 bis (4 hydroxy 3 methoxyphenyl) 1,6 heptadiene 3,5 dione … Wikipedia
Glutamate carboxypeptidase II — Reaction Scheme of NAAG Degradation by GCPII: GCPII + NAAG → GCPII NAAG complex → Glutamate + NAA Identifiers EC number … Wikipedia
Lesch–Nyhan syndrome — Lesch Nyhan syndrome Classification and external resources ICD 10 E79.1 ICD 9 277.2 … Wikipedia
Lyme disease microbiology — Lyme disease, or borreliosis, is caused by Gram negative spirochetal bacteria from the genus Borrelia , which has at least 37 known species, 12 of which are Lyme related, and an unknown number of genomic strains. Borrelia species known to cause… … Wikipedia